By Shoib Ahmad Baba, Nasheeman Ashraf
This booklet is a fabricated from years of study on saffron biology. It intends to offer a large yet concise evaluate of some of the points of apocarotenoid biosynthesis in Crocus sativus, its legislation and pharmacology .
Crocus sativusL. of relatives Iridaceae is a vital medicinal plant. The dried stigma of C. sativus flower is taken into account because the world's most costly spice. Saffron is the resources of exact carotenoid derived molecules referred to as apocarotenoids which come with crocin, crocetin, picrocrocin and safranal. those molecules are synthesized within the tissue and developmental degree particular demeanour. along with supplying color, aroma and flavour to the spice, those molecules have large medicinal value.
The ebook uncovers significant recommendations of apocarotenoids biosynthesis and offers deeper and extra entire realizing approximately their biotechnological and pharmacological applications.
The ebook is split into 3 sections –
The first part offers a common creation of C. sativus, its apocarotenoids, their biosynthesis, law and delivery. moment part offers information regarding the carotenoid cleavage dioxygenases (CCDs) that are the most important gamers in apocarotenoid biosynthesis. The class of plant CCDs, their constitution, response mechanism, biotechnological software are completely mentioned. the ultimate part offers with the most important pharmacological homes of C. sativus apocarotenoids, starting from their function as anticancer to their application as neuroprotective molecules.
This is a certainly one of its style booklet on Crocus sativus. It may be worthwhile for the researchers operating on Crocus sativus, students and in addition practitioners excited by extraction and bio-synthesis of the valuable scientific components.
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Extra info for Apocarotenoids of Crocus sativus L: From biosynthesis to pharmacology
2005) C. sativus (stigma) C. sativus (stigma) Akhondzadeh et al. (2010a) C. sativus (stigma) Donepezil Akhondzadeh et al. (2010b) C. sativus(stigma) C. sativus (stigma) Memantine Farokhnia et al. (2014) Crocin Talaei et al. 2 ml/kg) repaired the weakening activity of scopolamine (1 mg/kg) on memory in rats in the Morris water maze model. Besides it displayed no effect on intact memory. This was possibly because of its sedative effect through the BDZ site. Since ROS have shown to be involved in neurodegenerative diseases, antioxidants are believed to be promising neuroprotectors.
In South Asia saffron is widely used for liver, kidney, and vesica disease and for treatment of cholera. For the treatment of dermal diseases such as impetigo, saffron tincture is considered useful. 1. Traditional knowledge of medicinal properties of saffron has attracted scientists across the globe, and during the last few decades, several molecules with tremendous pharmacological importance have been isolated. These bioactive molecules include the unique apocarotenoids of saffron such as crocetin, crocin, picrocrocin, and safranal.
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